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MCA-205 is a weakly immunogenic fibrosarcoma-derived cell line that has been used in many studies to induce tumor-reactive T lymphocytes, the key aspect of adoptive immunotherapy (2). MCA-205 cells are widely utilized as stimulators for inducing cytokine expression (3).What is mca205 mouse fibrosarcoma cell line?
MCA205 mouse fibrosarcoma cell line is an excellent model for studying immune response to tumor cells and the development of targeted cancer immunotherapies. More>> MCA205 mouse fibrosarcoma cell line is an excellent model for studying immune response to tumor cells and the development of targeted cancer immunotherapies.Which research fields are MHC tetramers used in?
Which research fields are MHC tetramers used in? MHC tetramers are used for the detection and monitoring of antigen-specific T cells to study the adaptive immune response, including T cell development, disease progression, and evaluation of therapeutics, vaccinations, and other interventions that may have an impact on cellular immune responses.What is an MHC tetramer assay?
An MHC tetramer assay or simply tetramer assay or tetramer stain is a procedure developed at Stanford University School of Medicine that uses tetrameric proteins to detect and quantify T cells that are specific for a given antigen within a blood sample.