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What is in Iopidine ophthalmic solution?

IOPIDINE® 0.5% (apraclonidine ophthalmic solution) 0.5% As Base DESCRIPTION: IOPIDINE® 0.5% Ophthalmic Solution contains apraclonidine hydrochloride, an alpha adrenergic agonist, in a sterile isotonic solution for topical application to the eye. Apraclonidine hydrochloride is a white to off-white powder and is highly soluble in water.

How long does Iopidine stay in your system?

Studies of IOPIDINE 0.5% Ophthalmic Solution dosed one drop three times a day in both eyes for 10 days in normal volunteers yielded mean peak and trough concentrations of 0.9 ng/mL and 0.5 ng/mL, respectively. The half-life of IOPIDINE® 0.5% (apraclonidine ophthalmic solution) was calculated to be 8 hours.

Is Iopidine aqueous suppressant?

IOPIDINE 0.5% Ophthalmic Solution is an aqueous suppressing drug and the addition of a third aqueous suppressant may not significantly reduce IOP. The IOP lowering efficacy of IOPIDINE 0.5% Ophthalmic Solution diminishes over time in some patients.

What is Iopidine 5mg/ml used for?

IOPIDINE 5mg/ml is indicated for short-term adjunctive therapy of chronic glaucoma in patients on maximally tolerated medical therapy who require additional intraocular pressure (IOP) reduction to delay laser treatment or glaucoma surgery. The IOP lowering efficacy of IOPIDINE diminishes over time in most patients.

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